What does the presence of lymph node enlargement indicate?

The presence of lymph node enlargement is often an indication of infection in the body. Lymph nodes play a crucial role in the immune response; they act as filters for foreign substances and are integral in the body’s defense against pathogens such as bacteria and viruses. When an infection occurs, lymph nodes may become reactive and swell as they produce more lymphocytes—white blood cells that help combat infection. This swelling can also be accompanied by tenderness, especially if the nodes are actively fighting off an infection.

While lymph nodes may enlarge due to other conditions, such as cancer or allergies, infection is one of the most common and immediate triggers for lymphadenopathy. Therefore, observing lymph node enlargement typically prompts a healthcare provider to investigate potential infectious causes.